Singing related activation of DARPP-32+ Adult born Neurons in Zebra Finch HVC

Abstract: Neurogenesis in the avian brain produces new neurons (HVC NNs) into pre-existing neural circuits related to song production. Of the adult born NNs in HVC, 50% can be backfilled from RA while the other 50% cannot. The 50% that do not project to RA express DARPP-32, a phosphoprotein downstream of dopamine receptors.  DARPP-32+ NNs … Read more