Elucidating the Structure of the HU-Junction Complex
Abstract: HU, a histone-like protein, is one of the most abundant proteins in Escherichia coli and has significant roles in DNA packaging, recombination, replication, and repair. Previous studies have shown that HU binds with high affinity, in a non-sequence specific manner, to an important intermediate in recombination and repair, known as the Holliday or 4-Way … Read more