The nuclear Zn transporter ZIP11 is necessary for the proliferation of HeLa cells

Abstract Zinc (Zn) is an essential trace element as part of several biological processes, including transcriptional regulation, signaling, and catalysis. A subcellular network of Zn transporters ensures the adequate distribution of Zn to maintain homeostasis. Among these, the family of importers Zrt/Irt-like protein (ZIP) constitutes 14 members (ZIP1-ZIP14) that mobilize Zn into the cytosol. Expression of … Read more