Differential Roles of SWI/SNF Complexes in Metal Regulation
Abstract: SWI/SNF complexes play a major role in chromatin remodeling in mammalian cells. Mammalian DNA is compacted into chromatin by nucleosomes and other factors. The level of compaction is regulated largely by SWI/SNF complexes. These complexes remodel nucleosomes by displacing or evicting them, or by exchanging histones. By controlling which areas of the chromatin are … Read more