Modifying a Mini Protein with Two Conformational States to Instead Adopt Only One Conformation

Abstract: Our project is focused on the computationally-designed mini protein EHEE_rd2_0005. While the structure of this protein was previously determined in molecular dynamics simulations, structural knowledge derived from simulations are not as precise as real-world analysis. Members of our lab have previously attempted to obtain more accurate data with NMR spectroscopy but were unable to … Read more