Olfactory receptor coding sequences cause silencing of episomal constructs in the immortalized olfactory placode 6 cell line
Abstract: The mammalian olfactory system depends on a plethora of olfactory sensory neurons (OSNs), each exclusively expressing a single olfactory receptor (OR) gene, thus specializing each OSN to bind a specific range of odorant chemistries. Specifically in mice, the OR gene family is impressively comprised of >1,500 different OR genes, with expression being monogenic and … Read more