Protected: Progress towards Unearthing the Role of FrhA in Vibrio Cholerae Biosystems
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Molecular Biology & Biochemistry
Exploring the Binding and ATPase Activity of Msh2-Msh6 with Four Way Junction DNA
Abstract: Msh2-Msh6 is a eukaryotic ATP-dependent mismatch repair (MMR) protein that plays a key role in maintaining the fidelity of the genetic code. The protein recognizes and initiates repair for single base pair mismatches and short insertion/deletion loops (IDL). Fluorescence in solution assays have revealed that Msh2-Msh6 binds with the highest affinity to G:T mismatch … Read more
Demonstrating a Role for Histone H2A.Z in DNA Double Strand Break Repair and Chromosome Stability.
Abstract: The epigenome influences gene expression and chromosome dynamics without causing any changes in their DNA sequence. Heavy hitters in the world of epigenetics include the family of histone proteins, such as the nucleosome forming H2A, H2B, H3, and H4 proteins. Other histones include H1, present on linker DNA outside of the core histone octamer, … Read more