Role for Hippocampal δ-GABAA Receptors in the Effects of Adolescent Alcohol Exposure on Endocrine or Behavioral Stress Reactivity in Adulthood

Abstract: Adolescent binge drinking is linked to abnormal stress reactivity in adulthood and increased vulnerability to developing anxiety disorders. However, the neuronal mechanisms driving this relationship are unknown. Though previous research focused on plasticity of the hypothalamic-pituitary-adrenal (HPA) axis, recent work has highlighted the importance of the hippocampus in regulating both stress and anxiety. Our … Read more